DNA Vaccines: MHC II-Targeted Vaccine Protein Produced by Transfected Muscle Fibres Induces a Local Inflammatory Cell Infiltrate in Mice

Vaccination with naked DNA holds great promise but immunogenicity needs to be improved. DNA constructs encoding bivalent proteins that bind antigen-presenting cells (APC) for delivery of antigen have been shown to enhance T and B cell responses and protection in tumour challenge experiments. However...

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Detalles Bibliográficos
Autores principales: Løvås, Tom-Ole, Bruusgaard, Jo C., Øynebråten, Inger, Gundersen, Kristian, Bogen, Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191975/
https://www.ncbi.nlm.nih.gov/pubmed/25299691
http://dx.doi.org/10.1371/journal.pone.0108069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191975/
https://www.ncbi.nlm.nih.gov/pubmed/25299691
http://dx.doi.org/10.1371/journal.pone.0108069

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