Loss of the Endothelial Glucocorticoid Receptor Prevents the Therapeutic Protection Afforded by Dexamethasone after LPS

Glucocorticoids are normally regarded as anti-inflammatory therapy for a wide variety of conditions and have been used with some success in treating sepsis and sepsis-like syndromes. We previously demonstrated that mice lacking the glucocorticoid receptor in the endothelium (GR (EC KO) mice) are ext...

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Detalles Bibliográficos
Autores principales: Goodwin, Julie E., Feng, Yan, Velazquez, Heino, Zhou, Han, Sessa, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191990/
https://www.ncbi.nlm.nih.gov/pubmed/25299055
http://dx.doi.org/10.1371/journal.pone.0108126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191990/
https://www.ncbi.nlm.nih.gov/pubmed/25299055
http://dx.doi.org/10.1371/journal.pone.0108126

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