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QM/MM Molecular Dynamics Study of the Galactopyranose → Galactofuranose Reaction Catalysed by Trypanosoma cruzi UDP-Galactopyranose Mutase

The enzyme UDP-Galactopyranose Mutase (UGM) catalyses the conversion of galactopyranose into galactofuranose. It is known to be critical for the survival and proliferation of several pathogenic agents, both prokaryotic and eukaryotic. Among them is Trypanosoma cruzi, the parasite responsible for Cha...

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Detalles Bibliográficos
Autores principales: Pierdominici-Sottile, Gustavo, Cossio Pérez, Rodrigo, Galindo, Johan F., Palma, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192007/
https://www.ncbi.nlm.nih.gov/pubmed/25299056
http://dx.doi.org/10.1371/journal.pone.0109559