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Pou3f4-Mediated Regulation of Ephrin-B2 Controls Temporal Bone Development in the Mouse

The temporal bone encases conductive and sensorineural elements of the ear. Mutations of POU3F4 are associated with unique temporal bone abnormalities and X-linked mixed deafness (DFNX2/DFN3). However, the target genes and developmental processes controlled by POU3F4 transcription factor activity ha...

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Detalles Bibliográficos
Autores principales: Raft, Steven, Coate, Thomas M., Kelley, Matthew W., Crenshaw, E. Bryan, Wu, Doris K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192298/
https://www.ncbi.nlm.nih.gov/pubmed/25299585
http://dx.doi.org/10.1371/journal.pone.0109043