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HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP
BACKGROUND: HTLV-1 causes proliferation of clonal populations of infected T cells in vivo, each clone defined by a unique proviral integration site in the host genome. The proviral load is strongly correlated with odds of the inflammatory disease HTLV-1-associated myelopathy/tropical spastic parapar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192323/ https://www.ncbi.nlm.nih.gov/pubmed/25270762 http://dx.doi.org/10.1186/1743-422X-11-172 |