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HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP

BACKGROUND: HTLV-1 causes proliferation of clonal populations of infected T cells in vivo, each clone defined by a unique proviral integration site in the host genome. The proviral load is strongly correlated with odds of the inflammatory disease HTLV-1-associated myelopathy/tropical spastic parapar...

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Detalles Bibliográficos
Autores principales:	Niederer, Heather A, Laydon, Daniel J, Melamed, Anat, Elemans, Marjet, Asquith, Becca, Matsuoka, Masao, Bangham, Charles RM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192323/ https://www.ncbi.nlm.nih.gov/pubmed/25270762 http://dx.doi.org/10.1186/1743-422X-11-172

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