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Accounting for center in the Early External Cephalic Version trials: an empirical comparison of statistical methods to adjust for center in a multicenter trial with binary outcomes

BACKGROUND: Clustering of outcomes at centers involved in multicenter trials is a type of center effect. The Consolidated Standards of Reporting Trials Statement recommends that multicenter randomized controlled trials (RCTs) should account for center effects in their analysis, however most do not....

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Detalles Bibliográficos
Autores principales: Reitsma, Angela, Chu, Rong, Thorpe, Julia, McDonald, Sarah, Thabane, Lehana, Hutton, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192344/
https://www.ncbi.nlm.nih.gov/pubmed/25257928
http://dx.doi.org/10.1186/1745-6215-15-377