Efficient Gene Targeting in Golden Syrian Hamsters by the CRISPR/Cas9 System

The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research. Here, we report the first successful application of the CRISPR/Cas9 system to efficientl...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Zhiqiang, Li, Wei, Lee, Sang R., Meng, Qinggang, Shi, Bi, Bunch, Thomas D., White, Kenneth L., Kong, Il-Keun, Wang, Zhongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192357/
https://www.ncbi.nlm.nih.gov/pubmed/25299451
http://dx.doi.org/10.1371/journal.pone.0109755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192357/
https://www.ncbi.nlm.nih.gov/pubmed/25299451
http://dx.doi.org/10.1371/journal.pone.0109755

Ejemplares similares