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Efficient Gene Targeting in Golden Syrian Hamsters by the CRISPR/Cas9 System
The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research. Here, we report the first successful application of the CRISPR/Cas9 system to efficientl...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192357/ https://www.ncbi.nlm.nih.gov/pubmed/25299451 http://dx.doi.org/10.1371/journal.pone.0109755 |