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PCSD1, a new patient-derived model of bone metastatic prostate cancer, is castrate-resistant in the bone-niche
INTRODUCTION: Prostate cancer bone metastasis occurs in 50-90% of men with advanced disease for which there is no cure. Bone metastasis leads to debilitating fractures and severe bone pain. It is associated with therapy resistance and rapid decline. Androgen deprivation therapy (ADT) is standard of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192441/ https://www.ncbi.nlm.nih.gov/pubmed/25278011 http://dx.doi.org/10.1186/s12967-014-0275-1 |