PCSD1, a new patient-derived model of bone metastatic prostate cancer, is castrate-resistant in the bone-niche

INTRODUCTION: Prostate cancer bone metastasis occurs in 50-90% of men with advanced disease for which there is no cure. Bone metastasis leads to debilitating fractures and severe bone pain. It is associated with therapy resistance and rapid decline. Androgen deprivation therapy (ADT) is standard of...

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Detalles Bibliográficos
Autores principales: Godebu, Elana, Muldong, Michelle, Strasner, Amy, Wu, Christina N, Park, Seung Chol, Woo, Jason R, Ma, Wenxue, Liss, Michael A, Hirata, Takeshi, Raheem, Omer, Cacalano, Nicholas A, Kulidjian, Anna A, Jamieson, Christina AM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192441/
https://www.ncbi.nlm.nih.gov/pubmed/25278011
http://dx.doi.org/10.1186/s12967-014-0275-1

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