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Targeted In Vivo Inhibition of Specific Protein–Protein Interactions Using Recombinant Antibodies

With the growing availability of genomic sequence information, there is an increasing need for gene function analysis. Antibody-mediated “silencing” represents an intriguing alternative for the precise inhibition of a particular function of biomolecules. Here, we describe a method for selecting reco...

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Detalles Bibliográficos
Autores principales: Zábrady, Matej, Hrdinová, Vendula, Müller, Bruno, Conrad, Udo, Hejátko, Jan, Janda, Lubomír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192540/
https://www.ncbi.nlm.nih.gov/pubmed/25299686
http://dx.doi.org/10.1371/journal.pone.0109875