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Local Neutral Networks Help Maintain Inaccurately Replicating Ribozymes

The error threshold of replication limits the selectively maintainable genome size against recurrent deleterious mutations for most fitness landscapes. In the context of RNA replication a distinction between the genotypic and the phenotypic error threshold has been made; where the latter concerns th...

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Detalles Bibliográficos
Autores principales: Szilágyi, András, Kun, Ádám, Szathmáry, Eörs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192543/
https://www.ncbi.nlm.nih.gov/pubmed/25299454
http://dx.doi.org/10.1371/journal.pone.0109987