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Determination of Supplier-to-Supplier and Lot-to-Lot Variability in Glycation of Recombinant Human Serum Albumin Expressed in Oryza sativa

The use of different expression systems to produce the same recombinant human protein can result in expression-dependent chemical modifications (CMs) leading to variability of structure, stability and immunogenicity. Of particular interest are recombinant human proteins expressed in plant-based syst...

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Detalles Bibliográficos
Autores principales: Frahm, Grant E., Smith, Daryl G. S., Kane, Anita, Lorbetskie, Barry, Cyr, Terry D., Girard, Michel, Johnston, Michael J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192584/
https://www.ncbi.nlm.nih.gov/pubmed/25299339
http://dx.doi.org/10.1371/journal.pone.0109893