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Determination of Supplier-to-Supplier and Lot-to-Lot Variability in Glycation of Recombinant Human Serum Albumin Expressed in Oryza sativa
The use of different expression systems to produce the same recombinant human protein can result in expression-dependent chemical modifications (CMs) leading to variability of structure, stability and immunogenicity. Of particular interest are recombinant human proteins expressed in plant-based syst...
Autores principales: | Frahm, Grant E., Smith, Daryl G. S., Kane, Anita, Lorbetskie, Barry, Cyr, Terry D., Girard, Michel, Johnston, Michael J. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192584/ https://www.ncbi.nlm.nih.gov/pubmed/25299339 http://dx.doi.org/10.1371/journal.pone.0109893 |
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