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Intragenic Recombination Has a Critical Role on the Evolution of Legionella pneumophila Virulence-Related Effector sidJ

SidJ is a Dot/Icm effector involved in the trafficking or retention of ER-derived vesicles to Legionella pneumophila vacuoles whose mutation causes an observable growth defect, both in macrophage and amoeba hosts. Given the crucial role of this effector in L. pneumophila virulence we investigated th...

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Detalles Bibliográficos
Autores principales: Costa, Joana, Teixeira, Paulo Gonçalves, d'Avó, Ana Filipa, Júnior, Célio Santos, Veríssimo, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192588/
https://www.ncbi.nlm.nih.gov/pubmed/25299187
http://dx.doi.org/10.1371/journal.pone.0109840