Toxoplasma gondii Is Dependent on Glutamine and Alters Migratory Profile of Infected Host Bone Marrow Derived Immune Cells through SNAT2 and CXCR4 Pathways

The obligate intracellular parasite, Toxoplasma gondii, disseminates through its host inside infected immune cells. We hypothesize that parasite nutrient requirements lead to manipulation of migratory properties of the immune cell. We demonstrate that 1) T. gondii relies on glutamine for optimal inf...

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Detalles Bibliográficos
Autores principales: Lee, I-Ping, Evans, Andrew K., Yang, Cissy, Works, Melissa G., Kumar, Vineet, De Miguel, Zurine, Manley, Nathan C., Sapolsky, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192591/
https://www.ncbi.nlm.nih.gov/pubmed/25299045
http://dx.doi.org/10.1371/journal.pone.0109803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192591/
https://www.ncbi.nlm.nih.gov/pubmed/25299045
http://dx.doi.org/10.1371/journal.pone.0109803

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