mRNA Structural Constraints on EBNA1 Synthesis Impact on In Vivo Antigen Presentation and Early Priming of CD8(+) T Cells

Recent studies have shown that virally encoded mRNA sequences of genome maintenance proteins from herpesviruses contain clusters of unusual structural elements, G-quadruplexes, which modulate viral protein synthesis. Destabilization of these G-quadruplexes can override the inhibitory effect on self-...

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Detalles Bibliográficos
Autores principales: Tellam, Judy T., Zhong, Jie, Lekieffre, Lea, Bhat, Purnima, Martinez, Michelle, Croft, Nathan P., Kaplan, Warren, Tellam, Ross L., Khanna, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192603/
https://www.ncbi.nlm.nih.gov/pubmed/25299404
http://dx.doi.org/10.1371/journal.ppat.1004423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192603/
https://www.ncbi.nlm.nih.gov/pubmed/25299404
http://dx.doi.org/10.1371/journal.ppat.1004423

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