Dnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for Diseases

The correct establishment and maintenance of DNA methylation patterns are critical for mammalian development and the control of normal cell growth and differentiation. DNA methylation has profound effects on the mammalian genome, including transcriptional repression, modulation of chromatin structur...

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Detalles Bibliográficos
Autores principales: Walton, Emma L., Francastel, Claire, Velasco, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192629/
https://www.ncbi.nlm.nih.gov/pubmed/25198254
http://dx.doi.org/10.3390/biology3030578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192629/
https://www.ncbi.nlm.nih.gov/pubmed/25198254
http://dx.doi.org/10.3390/biology3030578

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