Counteracting suppression of CFTR and voltage-gated K(+) channels by a bacterial pathogenic factor with the natural product tannic acid

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) cause recurring bacterial infection in CF patients' lungs. However, the severity of CF lung disease correlates poorly with genotype. Antibiotic treatment helps dramatically prolong patients' life. The lung disease...

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Detalles Bibliográficos
Autores principales: Ramu, Yajamana, Xu, Yanping, Shin, Hyeon-Gyu, Lu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192643/
https://www.ncbi.nlm.nih.gov/pubmed/25313718
http://dx.doi.org/10.7554/eLife.03683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192643/
https://www.ncbi.nlm.nih.gov/pubmed/25313718
http://dx.doi.org/10.7554/eLife.03683

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