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Counteracting suppression of CFTR and voltage-gated K(+) channels by a bacterial pathogenic factor with the natural product tannic acid
Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) cause recurring bacterial infection in CF patients' lungs. However, the severity of CF lung disease correlates poorly with genotype. Antibiotic treatment helps dramatically prolong patients' life. The lung disease...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192643/ https://www.ncbi.nlm.nih.gov/pubmed/25313718 http://dx.doi.org/10.7554/eLife.03683 |