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Emerging Mechanistic Insights into AAA Complexes Regulating Proteasomal Degradation
The 26S proteasome is an integral element of the ubiquitin-proteasome system (UPS) and, as such, responsible for regulated degradation of proteins in eukaryotic cells. It consists of the core particle, which catalyzes the proteolysis of substrates into small peptides, and the regulatory particle, wh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192671/ https://www.ncbi.nlm.nih.gov/pubmed/25102382 http://dx.doi.org/10.3390/biom4030774 |