Metabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with Temozolomide

Inhibition of protein deacetylation enzymes, alone or in combination with standard chemotherapies, is an exciting addition to cancer therapy. We have investigated the effect of deacetylase inhibition on the metabolism of glioblastoma cells. (1)H NMR metabolomics analysis was used to determine the ma...

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Detalles Bibliográficos
Autores principales: Cuperlovic-Culf, Miroslava, Touaibia, Mohamed, St-Coeur, Patrick-Denis, Poitras, Julie, Morin, Pier Jr, Culf, Adrian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192694/
https://www.ncbi.nlm.nih.gov/pubmed/25222834
http://dx.doi.org/10.3390/metabo4030807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192694/
https://www.ncbi.nlm.nih.gov/pubmed/25222834
http://dx.doi.org/10.3390/metabo4030807

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