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Posttranslational regulation of Akt in human cancer

Akt regulates critical cellular processes including cell survival and proliferation, glucose metabolism, cell migration, cancer progression and metastasis through phosphorylation of a variety of downstream targets. The Akt pathway is one of the most prevalently hyperactivated signaling pathways in h...

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Detalles Bibliográficos
Autores principales: Chan, Chia-Hsin, Jo, Ukhyun, Kohrman, Abraham, Rezaeian, Abdol Hossein, Chou, Ping-Chieh, Logothetis, Christopher, Lin, Hui-Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192732/
https://www.ncbi.nlm.nih.gov/pubmed/25309720
http://dx.doi.org/10.1186/2045-3701-4-59