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Drug-Induced Gingival Overgrowth: The Genetic Dimension

BACKGROUND: Currently, the etiology of drug-induced gingival overgrowth is not entirely understood but is clearly multifactorial. Phenytoin, one of the common drugs implicated in gingival enlargement, is metabolized mainly by cytochrome P450 (CYP)2C9 and partly by CYP2C19. The CYP2C9 and CYP2C19 gen...

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Detalles Bibliográficos
Autores principales: Charles, Noronha Shyam Curtis, Chavan, Rahul, Moon, Ninad Joshirao, Nalla, Srinivas, Mali, Jaydeepchandra, Prajapati, Anchal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193156/
https://www.ncbi.nlm.nih.gov/pubmed/25317394
http://dx.doi.org/10.4103/1947-2714.141651