Instability of the insertional mutation in Cftr(TgH(neoim)Hgu )cystic fibrosis mouse model

BACKGROUND: A major boost to the cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic strains facilitated the search for modif...

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Detalles Bibliográficos
Autores principales: Charizopoulou, Nikoletta, Jansen, Silke, Dorsch, Martina, Stanke, Frauke, Dorin, Julia R, Hedrich, Hans-Jürgen, Tümmler, Burkhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419339/
https://www.ncbi.nlm.nih.gov/pubmed/15102331
http://dx.doi.org/10.1186/1471-2156-5-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419339/
https://www.ncbi.nlm.nih.gov/pubmed/15102331
http://dx.doi.org/10.1186/1471-2156-5-6

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