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Instability of the insertional mutation in Cftr(TgH(neoim)Hgu )cystic fibrosis mouse model
BACKGROUND: A major boost to the cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic strains facilitated the search for modif...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419339/ https://www.ncbi.nlm.nih.gov/pubmed/15102331 http://dx.doi.org/10.1186/1471-2156-5-6 |