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Computational Modeling Reveals that a Combination of Chemotaxis and Differential Adhesion Leads to Robust Cell Sorting during Tissue Patterning

Robust tissue patterning is crucial to many processes during development. The "French Flag" model of patterning, whereby naïve cells in a gradient of diffusible morphogen signal adopt different fates due to exposure to different amounts of morphogen concentration, has been the most widely...

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Detalles Bibliográficos
Autores principales: Tan, Rui Zhen, Chiam, Keng-Hwee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193783/
https://www.ncbi.nlm.nih.gov/pubmed/25302949
http://dx.doi.org/10.1371/journal.pone.0109286