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Aneugenic Effects of Epirubicin in Somatic and Germinal Cells of Male Mice
The ability of the antineoplastic agent epirubicin to induce aneuploidy and meiotic delay in the somatic and germinal cells of male mice was investigated by fluorescence in situ hybridization assay using labeled DNA probes and BrdU-incorporation assay. Mitomycin C and colchicine were used as positiv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193842/ https://www.ncbi.nlm.nih.gov/pubmed/25303090 http://dx.doi.org/10.1371/journal.pone.0109942 |