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Aneugenic Effects of Epirubicin in Somatic and Germinal Cells of Male Mice

The ability of the antineoplastic agent epirubicin to induce aneuploidy and meiotic delay in the somatic and germinal cells of male mice was investigated by fluorescence in situ hybridization assay using labeled DNA probes and BrdU-incorporation assay. Mitomycin C and colchicine were used as positiv...

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Detalles Bibliográficos
Autores principales: Attia, Sabry Mohamed, Ahmad, Sheikh Fayaz, Okash, Radwa Mohamed, Bakheet, Saleh Abdulrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193842/
https://www.ncbi.nlm.nih.gov/pubmed/25303090
http://dx.doi.org/10.1371/journal.pone.0109942