9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, Is a Potent Antifungal Agent That Inhibits the Growth of Cryptococcus neoformans by Regulating Gene Expression

In this study we explored the mode of action of KR-72, a 9-O-butyl-13-(4-isopropylbenzyl)berberine derivative previously shown to exhibit potent antifungal activity against a variety of human fungal pathogens. The DNA microarray data revealed that KR-72 treatment significantly changed the transcript...

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Detalles Bibliográficos
Autores principales: Bang, Soohyun, Kwon, Hyojeong, Hwang, Hyun Sook, Park, Ki Duk, Kim, Sung Uk, Bahn, Yong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193857/
https://www.ncbi.nlm.nih.gov/pubmed/25302492
http://dx.doi.org/10.1371/journal.pone.0109863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193857/
https://www.ncbi.nlm.nih.gov/pubmed/25302492
http://dx.doi.org/10.1371/journal.pone.0109863

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