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Valproic Acid and Fatalities in Children: A Review of Individual Case Safety Reports in VigiBase
INTRODUCTION: Valproic acid is an effective first line drug for the treatment of epilepsy. Hepatotoxicity is a rare and potentially fatal adverse reaction for this medicine. OBJECTIVE: Firstly to characterise valproic acid reports on children with fatal outcome and secondly to determine reporting ov...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193865/ https://www.ncbi.nlm.nih.gov/pubmed/25302991 http://dx.doi.org/10.1371/journal.pone.0108970 |