Cargando…

The effect of microneedles on the skin permeability and antitumor activity of topical 5-fluorouracil

Topical 5-fluorouracil (5-FU) is approved for the treatment of superficial basal cell carcinoma and actinic keratosis. However, 5-FU suffers from poor skin permeation. Microneedles have been successfully applied to improve the skin permeability of small and large molecules, and even nanoparticles, b...

Descripción completa

Detalles Bibliográficos
Autores principales: Naguib, Youssef W., Kumar, Amit, Cui, Zhengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193954/
https://www.ncbi.nlm.nih.gov/pubmed/25313350
http://dx.doi.org/10.1016/j.apsb.2013.12.013