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The effect of microneedles on the skin permeability and antitumor activity of topical 5-fluorouracil
Topical 5-fluorouracil (5-FU) is approved for the treatment of superficial basal cell carcinoma and actinic keratosis. However, 5-FU suffers from poor skin permeation. Microneedles have been successfully applied to improve the skin permeability of small and large molecules, and even nanoparticles, b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193954/ https://www.ncbi.nlm.nih.gov/pubmed/25313350 http://dx.doi.org/10.1016/j.apsb.2013.12.013 |