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The effect of microneedles on the skin permeability and antitumor activity of topical 5-fluorouracil

Topical 5-fluorouracil (5-FU) is approved for the treatment of superficial basal cell carcinoma and actinic keratosis. However, 5-FU suffers from poor skin permeation. Microneedles have been successfully applied to improve the skin permeability of small and large molecules, and even nanoparticles, b...

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Detalles Bibliográficos
Autores principales:	Naguib, Youssef W., Kumar, Amit, Cui, Zhengrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193954/ https://www.ncbi.nlm.nih.gov/pubmed/25313350 http://dx.doi.org/10.1016/j.apsb.2013.12.013

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