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Chromatin structure is distinct between coding and non-coding single nucleotide polymorphisms

BACKGROUND: Previous studies suggested that nucleosomes are enriched with single nucleotide polymorphisms (SNPs) in humans and that the occurrence of mutations is closely associated with CpG dinucleotides. We aimed to determine if the chromatin organization is genomic locus specific around SNPs, and...

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Detalles Bibliográficos
Autores principales: Liu, Hongde, Zhai, Jinchen, Luo, Kun, Liu, Lingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193957/
https://www.ncbi.nlm.nih.gov/pubmed/25282079
http://dx.doi.org/10.1186/1471-2199-15-22