Endothelial Na(+)/H(+) exchanger NHE1 participates in redox-sensitive leukocyte recruitment triggered by methylglyoxal

BACKGROUND: Excessive levels of methylglyoxal (MG) encountered in diabetes foster enhanced leukocyte-endothelial cell interactions, mechanisms of which are incompletely understood. MG genomically upregulates endothelial serum- and glucocorticoid-inducible kinase 1 (SGK1) which orchestrates leukocyte...

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Detalles Bibliográficos
Autores principales: Qadri, Syed M, Su, Yang, Cayabyab, Francisco S, Liu, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193979/
https://www.ncbi.nlm.nih.gov/pubmed/25270604
http://dx.doi.org/10.1186/s12933-014-0134-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193979/
https://www.ncbi.nlm.nih.gov/pubmed/25270604
http://dx.doi.org/10.1186/s12933-014-0134-7

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