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Silica nanoparticles enhance autophagic activity, disturb endothelial cell homeostasis and impair angiogenesis

BACKGROUND: Given that the effects of ultrafine fractions (<0.1 μm) on ischemic heart diseases (IHD) and other cardiovascular diseases are gaining attention, this study is aimed to explore the influence of silica nanoparticles (SiNPs)-induced autophagy on endothelial cell homeostasis and angiogen...

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Detalles Bibliográficos
Autores principales: Duan, Junchao, Yu, Yongbo, Yu, Yang, Li, Yang, Huang, Peili, Zhou, Xianqing, Peng, Shuangqing, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193984/
https://www.ncbi.nlm.nih.gov/pubmed/25266717
http://dx.doi.org/10.1186/s12989-014-0050-8