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Predicting co-complexed protein pairs using genomic and proteomic data integration

BACKGROUND: Identifying all protein-protein interactions in an organism is a major objective of proteomics. A related goal is to know which protein pairs are present in the same protein complex. High-throughput methods such as yeast two-hybrid (Y2H) and affinity purification coupled with mass spectr...

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Detalles Bibliográficos
Autores principales: Zhang, Lan V, Wong, Sharyl L, King, Oliver D, Roth, Frederick P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419405/
https://www.ncbi.nlm.nih.gov/pubmed/15090078
http://dx.doi.org/10.1186/1471-2105-5-38