Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses

Several proteins in the BRCA-Fanconi anemia (FA) pathway, such as FANCJ, BRCA1, and FANCD2, interact with mismatch repair (MMR) pathway factors, but the significance of this link remains unknown. Unlike the BRCA-FA pathway, the MMR pathway is not essential for cells to survive toxic DNA interstrand...

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Detalles Bibliográficos
Autores principales: Peng, Min, Xie, Jenny, Ucher, Anna, Stavnezer, Janet, Cantor, Sharon B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194102/
https://www.ncbi.nlm.nih.gov/pubmed/24966277
http://dx.doi.org/10.15252/embj.201387530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194102/
https://www.ncbi.nlm.nih.gov/pubmed/24966277
http://dx.doi.org/10.15252/embj.201387530

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