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New Pharmacological Perspectives for the Leptin Receptor in the Treatment of Obesity

After its discovery in 1994, leptin became the great hope as an anti-obesity treatment based on its ability to reduce food intake and increase energy expenditure. However, treating obese people with exogenous leptin was unsuccessful in most cases since most of them present already high circulating l...

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Detalles Bibliográficos
Autores principales: Roujeau, Clara, Jockers, Ralf, Dam, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195360/
https://www.ncbi.nlm.nih.gov/pubmed/25352831
http://dx.doi.org/10.3389/fendo.2014.00167