Folding Simulations for Proteins with Diverse Topologies Are Accessible in Days with a Physics-Based Force Field and Implicit Solvent

[Image: see text] The millisecond time scale needed for molecular dynamics simulations to approach the quantitative study of protein folding is not yet routine. One approach to extend the simulation time scale is to perform long simulations on specialized and expensive supercomputers such as Anton....

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Detalles Bibliográficos
Autores principales: Nguyen, Hai, Maier, James, Huang, He, Perrone, Victoria, Simmerling, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195377/
https://www.ncbi.nlm.nih.gov/pubmed/25255057
http://dx.doi.org/10.1021/ja5032776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195377/
https://www.ncbi.nlm.nih.gov/pubmed/25255057
http://dx.doi.org/10.1021/ja5032776

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