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Regional Heritability Mapping to identify loci underlying genetic variation of complex traits

BACKGROUND: Genome-wide association studies can have limited power to identify QTL, partly due to the stringent correction for multiple testing and low linkage-disequilibrium between SNPs and QTL. Regional Heritability Mapping (RHM) has been advanced as an alternative approach to capture underlying...

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Detalles Bibliográficos
Autores principales: Riggio, Valentina, Pong-Wong, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195407/
https://www.ncbi.nlm.nih.gov/pubmed/25519517
http://dx.doi.org/10.1186/1753-6561-8-S5-S3