Synthesis, characterization and RHF/ab initio simulations of 2-amino-1,3,4-thiadiazole and its annulated ring junction pyrimidine derivatives

Michael addition reaction of the 2-amino-1,3,4-thiadiazole to chalcone as biselectrophile afforded 5,7-diphenyl-6-[1,3-diphenylpropan-1-on-3-yl][1,3,4]thiadiazolo[3,2-a]pyrimidine (3) instead of 5,7-diphenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine (5) via further Michael addition at C(5) in pyrimidin...

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Detalles Bibliográficos
Autores principales: Hamama, Wafaa S., Gouda, Moustafa A., Soliman, Mamdouh S., Badr, Marwa H., Zoorob, Hanafi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195460/
https://www.ncbi.nlm.nih.gov/pubmed/25685403
http://dx.doi.org/10.1016/j.jare.2012.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195460/
https://www.ncbi.nlm.nih.gov/pubmed/25685403
http://dx.doi.org/10.1016/j.jare.2012.01.005

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