Sustained Induction of Collagen Synthesis by TGF-β Requires Regulated Intramembrane Proteolysis of CREB3L1

CREB3L1 (cAMP response element binding protein 3-like 1), a transcription factor synthesized as a membrane-bound precursor and activated through Regulated Intramembrane Proteolysis (RIP), is essential for collagen production by osteoblasts during bone development. Here, we show that TGF-β (transform...

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Detalles Bibliográficos
Autores principales: Chen, Qiuyue, Lee, Ching-En, Denard, Bray, Ye, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195586/
https://www.ncbi.nlm.nih.gov/pubmed/25310401
http://dx.doi.org/10.1371/journal.pone.0108528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195586/
https://www.ncbi.nlm.nih.gov/pubmed/25310401
http://dx.doi.org/10.1371/journal.pone.0108528

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