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Suppressor of Cytokine Signaling 1 Counteracts Rhesus Macaque TRIM5α-Induced Inhibition of Human Immunodeficiency Virus Type-1 Production

Old world monkey TRIM5α is a host factor that restricts human immunodeficiency virus type-1 (HIV-1) infection. Previously, we reported that rhesus macaque TRIM5α (RhTRIM5α) restricts HIV-1 production by inducing degradation of precursor Gag. Since suppressor of cytokine signaling 1 (SOCS1) is known...

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Detalles Bibliográficos
Autores principales: Sukegawa, Sayaka, Sakuma, Ryuta, Ohmine, Seiga, Takeuchi, Hiroaki, Ikeda, Yasuhiro, Yamaoka, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195675/
https://www.ncbi.nlm.nih.gov/pubmed/25310711
http://dx.doi.org/10.1371/journal.pone.0109640