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The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have p...

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Detalles Bibliográficos
Autores principales: Schuck, Robert N., Zha, Weibin, Edin, Matthew L., Gruzdev, Artiom, Vendrov, Kimberly C., Miller, Tricia M., Xu, Zhenghong, Lih, Fred B., DeGraff, Laura M., Tomer, Kenneth B., Jones, H. Michael, Makowski, Liza, Huang, Leaf, Poloyac, Samuel M., Zeldin, Darryl C., Lee, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195706/
https://www.ncbi.nlm.nih.gov/pubmed/25310404
http://dx.doi.org/10.1371/journal.pone.0110162