Confirmation of Childhood Acute Lymphoblastic Leukemia Variants, ARID5B and IKZF1, and Interaction with Parental Environmental Exposures

Genome wide association studies (GWAS) have established association of ARID5B and IKZF1 variants with childhood acute lymphoblastic leukemia (ALL). Epidemiological studies suggest that environmental factors alone appear to make a relatively minor contribution to disease risk. The polygenic nature of...

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Detalles Bibliográficos
Autores principales: Evans, Tiffany-Jane, Milne, Elizabeth, Anderson, Denise, de Klerk, Nicholas H., Jamieson, Sarra E., Talseth-Palmer, Bente A., Bowden, Nikola A., Holliday, Elizabeth G., Rudant, Jérémie, Orsi, Laurent, Richardson, Ebony, Lavis, Laura, Catchpoole, Daniel, Attia, John R., Armstrong, Bruce K., Clavel, Jacqueline, Scott, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195717/
https://www.ncbi.nlm.nih.gov/pubmed/25310577
http://dx.doi.org/10.1371/journal.pone.0110255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195717/
https://www.ncbi.nlm.nih.gov/pubmed/25310577
http://dx.doi.org/10.1371/journal.pone.0110255

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