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P2X7 Receptor Modulates Inflammatory and Functional Pulmonary Changes Induced by Silica
Silicosis is an occupational lung disease, characterized by irreversible and progressive fibrosis. Silica exposure leads to intense lung inflammation, reactive oxygen production, and extracellular ATP (eATP) release by macrophages. The P2X7 purinergic receptor is thought to be an important immunomod...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195726/ https://www.ncbi.nlm.nih.gov/pubmed/25310682 http://dx.doi.org/10.1371/journal.pone.0110185 |