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P2X7 Receptor Modulates Inflammatory and Functional Pulmonary Changes Induced by Silica

Silicosis is an occupational lung disease, characterized by irreversible and progressive fibrosis. Silica exposure leads to intense lung inflammation, reactive oxygen production, and extracellular ATP (eATP) release by macrophages. The P2X7 purinergic receptor is thought to be an important immunomod...

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Detalles Bibliográficos
Autores principales:	Monção-Ribeiro, Leonardo C., Faffe, Débora S., Santana, Patrícia T., Vieira, Flávia S., da Graça, Carolyne Lalucha A. L., Marques-da-Silva, Camila, Machado, Mariana N., Caruso-Neves, Celso, Zin, Walter A., Borojevic, Radovan, Takiya, Christina M., Coutinho-Silva, Robson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195726/ https://www.ncbi.nlm.nih.gov/pubmed/25310682 http://dx.doi.org/10.1371/journal.pone.0110185

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