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Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy

We sought to determine the mechanisms underlying failure of muscle regeneration that is observed in dystrophic muscle through hypothesis generation using muscle profiling data (human dystrophy and murine regeneration). We found that transforming growth factor β–centered networks strongly associated...

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Detalles Bibliográficos
Autores principales: Dadgar, Sherry, Wang, Zuyi, Johnston, Helen, Kesari, Akanchha, Nagaraju, Kanneboyina, Chen, Yi-Wen, Hill, D. Ashley, Partridge, Terence A., Giri, Mamta, Freishtat, Robert J., Nazarian, Javad, Xuan, Jianhua, Wang, Yue, Hoffman, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195829/
https://www.ncbi.nlm.nih.gov/pubmed/25313409
http://dx.doi.org/10.1083/jcb.201402079